Family ID	FD00396
Protein Name	Cubilin
UniProt ID	O60494
Prosequence Length Range (aa)	12
Preproprotein Length Range(aa)	3623
Preproprotein pI Range	5.14
Preproprotein Molecular Weight Range (D)	398736.28
Prosequence pI Range (D)	6.33
Prosequence Molecular Weight Range	1456.62
Domains	cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00041 : cd00054 : cd00054 : cd00054 : cd00054 : cd22201 : cl00049 : pfam00431 : pfam12947 : pfam12947
Organisms	Homo sapiens (Human)
Functions	calcium ion binding; cargo receptor activity; cobalamin binding; protein homodimerization activity; signaling receptor activity
Cellular Localization	apical plasma membrane; brush border membrane; clathrin-coated pit; cytosol; endocytic vesicle; endoplasmic reticulum; endosome membrane; extracellular exosome; extrinsic component of external side of plasma membrane; Golgi apparatus; lysosomal lumen; lysosomal membrane; membrane; plasma membrane; receptor complex
Processes	cholesterol metabolic process; cobalamin metabolic process; cobalamin transport; high-density lipoprotein particle clearance; lipoprotein transport; receptor-mediated endocytosis; response to bacterium; tissue homeostasis; vitamin D metabolic process
Common Name	Cubilin