Details of family id : FD00334
Family ID |
FD00334 |
Protein Name |
Protein Wnt-5a |
UniProt ID |
P22725
|
Prosequence Length Range (aa) |
24
|
Preproprotein Length Range(aa) |
380 |
Preproprotein pI Range |
8.83 |
Preproprotein Molecular Weight Range (D) |
42309.42 |
Prosequence pI Range (D) |
3.79 |
Prosequence Molecular Weight Range |
2782.14 |
Domains |
cd19347 |
Organisms |
Mus musculus (Mouse) |
Functions |
chemoattractant activity involved in axon guidance; cytokine activity; frizzled binding; protein domain specific binding; receptor tyrosine kinase-like orphan receptor binding; signaling receptor binding |
Cellular Localization |
cell surface; cytoplasm; endoplasmic reticulum lumen; extracellular matrix; extracellular region; extracellular space; glutamatergic synapse; postsynapse |
Processes |
activation of GTPase activity; activation of JUN kinase activity; activation of MAPK activity; activation of protein kinase B activity; ameboidal-type cell migration; animal organ morphogenesis; anterior/posterior axis specification; embryo; anterior/posterior pattern specification; atrial septum development; axis elongation; axon guidance; axonal fasciculation; axonogenesis; canonical Wnt signaling pathway; cartilage development; cell fate commitment; cell migration; cell-cell signaling; cellular protein localization; cellular response to calcium ion; cellular response to interferon-gamma; cellular response to lipopolysaccharide; cellular response to molecule of bacterial origin; cellular response to transforming growth factor beta stimulus; cervix development; chemoattraction of serotonergic neuron axon; chemorepulsion of dopaminergic neuron axon; cochlea morphogenesis; convergent extension; convergent extension involved in axis elongation; convergent extension involved in organogenesis; determination of left/right symmetry; development of primary male sexual characteristics; digestive tract morphogenesis; dopaminergic neuron differentiation; embryonic digit morphogenesis; embryonic limb morphogenesis; embryonic skeletal system development; epithelial cell proliferation involved in mammary gland duct elongation; establishment of epithelial cell apical/basal polarity; establishment of planar polarity; face development; genitalia development; heart looping; hematopoietic stem cell proliferation; hindgut morphogenesis; hypophysis morphogenesis; inner ear morphogenesis; JNK cascade; keratinocyte differentiation; kidney development; lateral sprouting involved in mammary gland duct morphogenesis; limb morphogenesis; lung development; male gonad development; mammary gland branching involved in thelarche; melanocyte proliferation; mesenchymal-epithelial cell signaling; mesodermal to mesenchymal transition involved in gastrulation; midbrain development; midbrain dopaminergic neuron differentiation; midgut development; morphogenesis of an epithelium; negative chemotaxis; negative regulation of apoptotic process; negative regulation of axon extension involved in axon guidance; negative regulation of BMP signaling pathway; negative regulation of canonical Wnt signaling pathway; negative regulation of cell proliferation in midbrain; negative regulation of epithelial cell proliferation; negative regulation of fat cell differentiation; negative regulation of fibroblast growth factor receptor signaling pathway; negative regulation of melanin biosynthetic process; negative regulation of mesenchymal cell proliferation; negative regulation of prostatic bud formation; negative regulation of synapse assembly; negative regulation of transcription; DNA-templated; neural tube closure; neural tube development; neurogenesis; neuron differentiation; neuron projection morphogenesis; non-canonical Wnt signaling pathway; non-canonical Wnt signaling pathway via JNK cascade; notochord morphogenesis; olfactory bulb interneuron development; paraxial mesoderm formation; pericardium morphogenesis; planar cell polarity pathway involved in axis elongation; planar cell polarity pathway involved in axon guidance; planar cell polarity pathway involved in cardiac muscle tissue morphogenesis; planar cell polarity pathway involved in cardiac right atrium morphogenesis; planar cell polarity pathway involved in gastrula mediolateral intercalation; planar cell polarity pathway involved in neural tube closure; planar cell polarity pathway involved in outflow tract morphogenesis; planar cell polarity pathway involved in pericardium morphogenesis; planar cell polarity pathway involved in ventricular septum morphogenesis; positive regulation of angiogenesis; positive regulation of cartilage development; positive regulation of cell population proliferation; positive regulation of cell-cell adhesion; positive regulation of cell-cell adhesion mediated by cadherin; positive regulation of chemokine production; positive regulation of cytokine production; positive regulation of cytokine production involved in immune response; positive regulation of endocytosis; positive regulation of endothelial cell migration; positive regulation of endothelial cell proliferation; positive regulation of epithelial cell proliferation; positive regulation of fibroblast proliferation; positive regulation of gene expression; positive regulation of GTPase activity; positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway; positive regulation of inflammatory response; positive regulation of interferon-gamma production; positive regulation of interleukin-1 beta production; positive regulation of interleukin-6 production; positive regulation of interleukin-8 production; positive regulation of JNK cascade; positive regulation of JUN kinase activity; positive regulation of macrophage activation; positive regulation of macrophage cytokine production; positive regulation of meiotic nuclear division; positive regulation of mesenchymal cell proliferation; positive regulation of neuron death; positive regulation of neuron projection arborization; positive regulation of neuron projection development; positive regulation of NF-kappaB transcription factor activity; positive regulation of non-canonical Wnt signaling pathway; positive regulation of ossification; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-threonine phosphorylation; positive regulation of protein binding; positive regulation of protein catabolic process; positive regulation of protein kinase activity; positive regulation of protein kinase C activity; positive regulation of protein kinase C signaling; positive regulation of protein phosphorylation; positive regulation of response to cytokine stimulus; positive regulation of T cell chemotaxis; positive regulation of thymocyte apoptotic process; positive regulation of timing of anagen; positive regulation of transcription by RNA polymerase II; positive regulation of transcription; positive regulation of tumor necrosis factor production; positive regulation of type I interferon-mediated signaling pathway; post-anal tail morphogenesis; primary heart field specification; primitive streak formation; protein phosphorylation; regulation of branching involved in mammary gland duct morphogenesis; regulation of cellular protein localization; regulation of I-kappaB kinase/NF-kappaB signaling; regulation of postsynapse organization; regulation of postsynaptic cytosolic calcium ion concentration; regulation of protein localization; regulation of synapse organization; secondary heart field specification; secondary palate development; signal transduction; somite development; somitogenesis; tube closure; type B pancreatic cell development; urinary bladder development; uterus development; vagina development; ventricular septum development; Wnt signaling pathway; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation; calcium modulating pathway; planar cell polarity pathway; wound healing |
Common Name |
protein Wnt |