Details of family id : FD00226
| Family ID |
FD00226 |
| Protein Name |
Furin |
| UniProt ID |
P09958
|
| Prosequence Length Range (aa) |
81
|
| Preproprotein Length Range(aa) |
794 |
| Preproprotein pI Range |
6.01 |
| Preproprotein Molecular Weight Range (D) |
86678.01 |
| Prosequence pI Range (D) |
11.93 |
| Prosequence Molecular Weight Range |
9570.96 |
| Domains |
cd04059 : pfam01483 : pfam16470 : smart00261 : smart00261 |
| Organisms |
Homo sapiens (Human) |
| Functions |
endopeptidase activity; metal ion binding; nerve growth factor binding; peptidase activity; peptide binding; protease binding; serine-type endopeptidase activity; serine-type endopeptidase inhibitor activity |
| Cellular Localization |
cell surface; endoplasmic reticulum; endosome membrane; extracellular exosome; extracellular region; Golgi lumen; Golgi membrane; integral component of Golgi membrane; membrane; membrane raft; plasma membrane; trans-Golgi network; trans-Golgi network transport vesicle |
| Processes |
amyloid fibril formation; blastocyst formation; collagen catabolic process; cornification; dibasic protein processing; extracellular matrix disassembly; extracellular matrix organization; negative regulation of inflammatory response to antigenic stimulus; negative regulation of low-density lipoprotein particle receptor catabolic process; negative regulation of transforming growth factor beta1 production; nerve growth factor processing; nerve growth factor production; peptide biosynthetic process; peptide hormone processing; positive regulation of membrane protein ectodomain proteolysis; positive regulation of transforming growth factor beta1 activation; protein processing; regulation of cholesterol transport; regulation of endopeptidase activity; regulation of lipoprotein lipase activity; regulation of protein catabolic process; regulation of signal transduction; secretion by cell; signal peptide processing; transforming growth factor beta receptor signaling pathway; viral life cycle; viral protein processing; zymogen activation; zymogen inhibition |
| Common Name |
Furin |
