Details of family id : FD00195
| Family ID |
FD00195 |
| Protein Name |
Forkhead box protein P3 |
| UniProt ID |
Q9BZS1
Q99JB6
|
| Prosequence Length Range (aa) |
12-14
|
| Preproprotein Length Range(aa) |
429-431 |
| Preproprotein pI Range |
9.41-9.52 |
| Preproprotein Molecular Weight Range (D) |
47244.28-47346.47 |
| Prosequence pI Range (D) |
8.94-10.35 |
| Prosequence Molecular Weight Range |
1330.5-1483.62 |
| Domains |
cd20066 : pfam16159 |
| Organisms |
Homo sapiens (Human); Mus musculus (Mouse) |
| Functions |
DNA binding; DNA-binding transcription factor activity; RNA polymerase II-specific; DNA-binding transcription repressor activity; histone acetyltransferase binding; histone deacetylase binding; metal ion binding; NF-kappaB binding; NFAT protein binding; protein homodimerization activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; sequence-specific DNA binding; sequence-specific double-stranded DNA binding; transcription corepressor activity; identical protein binding |
| Cellular Localization |
chromatin; cytoplasm; nucleoplasm; nucleus; protein-containing complex |
| Processes |
B cell homeostasis; CD4-positive; CD25-positive; alpha-beta regulatory T cell lineage commitment; chromatin remodeling; gene expression; myeloid cell homeostasis; negative regulation of activated T cell proliferation; negative regulation of cell population proliferation; negative regulation of chronic inflammatory response; negative regulation of CREB transcription factor activity; negative regulation of cytokine production; negative regulation of DNA-binding transcription factor activity; negative regulation of histone acetylation; negative regulation of histone deacetylation; negative regulation of immune response; negative regulation of interferon-gamma production; negative regulation of interleukin-10 production; negative regulation of interleukin-17 production; negative regulation of interleukin-2 production; negative regulation of interleukin-4 production; negative regulation of interleukin-5 production; negative regulation of interleukin-6 production; negative regulation of isotype switching to IgE isotypes; negative regulation of NF-kappaB transcription factor activity; negative regulation of T cell cytokine production; negative regulation of T cell proliferation; negative regulation of T-helper 17 cell differentiation; negative regulation of transcription by RNA polymerase II; negative regulation of transcription; DNA-templated; negative regulation of tumor necrosis factor production; positive regulation of CD4-positive; alpha-beta regulatory T cell differentiation; positive regulation of histone acetylation; positive regulation of immature T cell proliferation in thymus; positive regulation of interleukin-4 production; positive regulation of peripheral T cell tolerance induction; positive regulation of T cell anergy; positive regulation of transcription by RNA polymerase II; positive regulation of transcription; positive regulation of transforming growth factor beta1 production; regulation of isotype switching to IgG isotypes; regulation of regulatory T cell differentiation; regulation of T cell anergy; regulation of transcription by RNA polymerase II; regulation of transcription; regulation of Wnt signaling pathway; response to lipopolysaccharide; response to virus; T cell activation; T cell homeostasis; T cell mediated immunity; T cell receptor signaling pathway; tolerance induction to self antigen; negative regulation of defense response to virus; negative regulation of gene expression; negative regulation of inflammatory response; negative regulation of lymphocyte proliferation; positive regulation of gene expression; positive regulation of regulatory T cell differentiation; positive regulation of T cell tolerance induction; regulation of immunoglobulin production; tolerance induction |
| Common Name |
Forkhead box protein |
