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Details of family id : FD00165

Family ID FD00165
Protein Name Parathyroid hormone
UniProt ID P01269 P01270
Prosequence Length Range (aa) 6
Preproprotein Length Range(aa) 120
Preproprotein pI Range 9.72-9.88
Preproprotein Molecular Weight Range (D) 12852.11-12861.08
Prosequence pI Range (D) 11.26
Prosequence Molecular Weight Range 744.94-769.0
Domains smart00087
Organisms Sus scrofa (Pig); Homo sapiens (Human)
Functions hormone activity; parathyroid hormone receptor binding; peptide hormone receptor binding; protein N-terminus binding; type 1 parathyroid hormone receptor binding; receptor ligand activity
Cellular Localization extracellular space; extracellular region
Processes activation of phospholipase C activity; adenylate cyclase-activating G protein-coupled receptor signaling pathway; cell-cell signaling; cellular calcium ion homeostasis; cellular macromolecule biosynthetic process; homeostasis of number of cells within a tissue; magnesium ion homeostasis; negative regulation of apoptotic process in bone marrow cell; negative regulation of gene expression; phosphate ion homeostasis; positive regulation of bone mineralization; positive regulation of cell proliferation in bone marrow; positive regulation of glucose import; positive regulation of glycogen biosynthetic process; positive regulation of inositol phosphate biosynthetic process; positive regulation of osteoclast proliferation; positive regulation of signal transduction; positive regulation of transcription by RNA polymerase II; bone resorption; cAMP metabolic process; G protein-coupled receptor signaling pathway; hormone-mediated apoptotic signaling pathway; negative regulation of bone mineralization involved in bone maturation; negative regulation of chondrocyte differentiation; negative regulation of inflammatory response to antigenic stimulus; regulation of gene expression; response to cadmium ion; response to drug; response to ethanol; response to fibroblast growth factor; response to lead ion; response to parathyroid hormone; response to vitamin D; Rho protein signal transduction; skeletal system development
Common Name Parathyroid hormone