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Details of family id : FD00132

Family ID FD00132
Protein Name Pro-adrenomedullin; Skin calcitonin gene-related peptide
UniProt ID P43145 P81564
Prosequence Length Range (aa) 36-47
Preproprotein Length Range(aa) 120-185
Preproprotein pI Range 9.49-10.81
Preproprotein Molecular Weight Range (D) 12438.29-20636.4
Prosequence pI Range (D) 5.49-8.79
Prosequence Molecular Weight Range 3941.33-4975.41
Domains pfam00214
Organisms Rattus norvegicus (Rat); Phyllomedusa bicolor (Two-colored leaf frog) (Rana bicolor)
Functions adrenomedullin receptor binding; hormone activity
Cellular Localization cytoplasm; extracellular space; extracellular region
Processes adenylate cyclase-activating G protein-coupled receptor signaling pathway; adrenomedullin receptor signaling pathway; aging; amylin receptor signaling pathway; androgen metabolic process; animal organ regeneration; branching involved in labyrinthine layer morphogenesis; calcium ion homeostasis; cAMP-mediated signaling; developmental growth; female pregnancy; G protein-coupled receptor internalization; heart development; hormone secretion; negative regulation of cell population proliferation; negative regulation of vascular permeability; negative regulation of vasoconstriction; neural tube closure; neuron projection regeneration; odontogenesis of dentin-containing tooth; positive regulation of angiogenesis; positive regulation of apoptotic process; positive regulation of cell population proliferation; positive regulation of cytosolic calcium ion concentration; positive regulation of heart rate; positive regulation of vasculogenesis; receptor internalization; regulation of systemic arterial blood pressure; regulation of the force of heart contraction; regulation of urine volume; response to cold; response to glucocorticoid; response to hypoxia; response to insulin; response to lipopolysaccharide; response to organic substance; response to starvation; response to wounding; spongiotrophoblast layer development; vascular associated smooth muscle cell development; vasculogenesis;
Common Name proadrenomedullin; skin calcitonin gene related peptide