Details of family id : FD00131
| Family ID |
FD00131 |
| Protein Name |
Caspase-1; Caspase-3 |
| UniProt ID |
O02002
P42574
|
| Prosequence Length Range (aa) |
13-19
|
| Preproprotein Length Range(aa) |
277-323 |
| Preproprotein pI Range |
6.09-7.63 |
| Preproprotein Molecular Weight Range (D) |
31607.88-35926.75 |
| Prosequence pI Range (D) |
4.14-6.48 |
| Prosequence Molecular Weight Range |
1319.43-2113.41 |
| Domains |
smart00115 |
| Organisms |
Drosophila melanogaster (Fruit fly); Homo sapiens (Human) |
| Functions |
BIR domain binding; cysteine-type endopeptidase activity; cysteine-type endopeptidase activity involved in apoptotic process; cysteine-type endopeptidase activity involved in execution phase of apoptosis; aspartic-type endopeptidase activity; cyclin-dependent protein serine/threonine kinase inhibitor activity; cysteine-type endopeptidase activity involved in apoptotic signaling pathway; death receptor binding; peptidase activity; phospholipase A2 activator activity; protease binding; protein-containing complex binding |
| Cellular Localization |
cytoplasm; cytosol; messenger ribonucleoprotein complex; mitochondrion; neuronal cell body; neuronal ribonucleoprotein granule; death-inducing signaling complex; membrane raft; nucleoplasm; nucleus |
| Processes |
apoptotic process; cellular response to starvation; cytoplasmic transport; nurse cell to oocyte; execution phase of apoptosis; multicellular organism development; negative regulation of apoptotic process; negative regulation of neuromuscular synaptic transmission; neuron remodeling; nurse cell apoptotic process; oogenesis; ovarian nurse cell to oocyte transport; positive regulation of autophagy; positive regulation of macroautophagy; programmed cell death; programmed cell death involved in cell development; anterior neural tube closure; apoptotic DNA fragmentation; apoptotic signaling pathway; axonal fasciculation; B cell homeostasis; cell fate commitment; cellular response to DNA damage stimulus; cellular response to staurosporine; cytokine-mediated signaling pathway; erythrocyte differentiation; extrinsic apoptotic signaling pathway in absence of ligand; glial cell apoptotic process; heart development; hippo signaling; hippocampus development; intrinsic apoptotic signaling pathway in response to osmotic stress; keratinocyte differentiation; learning or memory; leukocyte apoptotic process; luteolysis; negative regulation of activated T cell proliferation; negative regulation of B cell proliferation; neuron apoptotic process; neuron differentiation; neurotrophin TRK receptor signaling pathway; platelet formation; positive regulation of amyloid-beta formation; positive regulation of apoptotic process; positive regulation of neuron apoptotic process; protein processing; proteolysis; regulation of macroautophagy; regulation of protein stability; response to amino acid; response to antibiotic; response to cobalt ion; response to drug; response to estradiol; response to glucocorticoid; response to glucose; response to hydrogen peroxide; response to hypoxia; response to lipopolysaccharide; response to nicotine; response to tumor necrosis factor; response to UV; response to X-ray; sensory perception of sound; striated muscle cell differentiation; T cell homeostasis; wound healing |
| Common Name |
Caspase |
