Details of family id : FD00127
| Family ID |
FD00127 |
| Protein Name |
Collagen alpha-1(I) chain |
| UniProt ID |
P02452
P02453
|
| Prosequence Length Range (aa) |
139-246
|
| Preproprotein Length Range(aa) |
1463-1464 |
| Preproprotein pI Range |
5.6 |
| Preproprotein Molecular Weight Range (D) |
138938.49-138941.5 |
| Prosequence pI Range (D) |
4.11-5.31 |
| Prosequence Molecular Weight Range |
14241.68-27549.79 |
| Domains |
cl35613 : pfam00093 : pfam01391 : pfam01391 : pfam01410 |
| Organisms |
Homo sapiens (Human); Bos taurus (Bovine) |
| Functions |
extracellular matrix structural constituent; extracellular matrix structural constituent conferring tensile strength; identical protein binding; metal ion binding; platelet-derived growth factor binding; protease binding |
| Cellular Localization |
collagen type I trimer; collagen-containing extracellular matrix; cytoplasm; endoplasmic reticulum lumen; extracellular matrix; extracellular region; extracellular space; Golgi apparatus; secretory granule |
| Processes |
blood coagulation; blood vessel development; bone trabecula formation; cartilage development involved in endochondral bone morphogenesis; cellular response to amino acid stimulus; cellular response to epidermal growth factor stimulus; cellular response to fibroblast growth factor stimulus; cellular response to fluoride; cellular response to mechanical stimulus; cellular response to retinoic acid; cellular response to transforming growth factor beta stimulus; cellular response to tumor necrosis factor; cellular response to vitamin E; collagen biosynthetic process; collagen fibril organization; collagen-activated tyrosine kinase receptor signaling pathway; embryonic skeletal system development; endochondral ossification; extracellular matrix organization; face morphogenesis; intramembranous ossification; leukocyte migration; negative regulation of cell-substrate adhesion; ossification; osteoblast differentiation; platelet activation; positive regulation of canonical Wnt signaling pathway; positive regulation of cell migration; positive regulation of epithelial to mesenchymal transition; positive regulation of transcription; DNA-templated; protein localization to nucleus; protein transport; regulation of immune response; response to cAMP; response to corticosteroid; response to drug; response to estradiol; response to hydrogen peroxide; response to hyperoxia; response to mechanical stimulus; response to peptide hormone; sensory perception of sound; skeletal system development; skin development; skin morphogenesis; tooth eruption; tooth mineralization; visual perception |
| Common Name |
Collagen alpha chain |
