Details of family id : FD00052
| Family ID |
FD00052 |
| Protein Name |
Urocortin-2; Corticoliberin; Diuretic hormone 44 |
| UniProt ID |
Q99ML8
P06296
P01143
E2A6P1
P06850
|
| Prosequence Length Range (aa) |
48-129
|
| Preproprotein Length Range(aa) |
120-196 |
| Preproprotein pI Range |
6.43-10.38 |
| Preproprotein Molecular Weight Range (D) |
12310.27-21421.76 |
| Prosequence pI Range (D) |
4.14-11.25 |
| Prosequence Molecular Weight Range |
4959.32-14010.87 |
| Domains |
pfam00473 |
| Organisms |
Mus musculus (Mouse); Sus scrofa (Pig); Rattus norvegicus (Rat); Camponotus floridanus (Florida carpenter ant); Homo sapiens (Human) |
| Functions |
corticotropin-releasing hormone receptor 2 binding; corticotropin-releasing hormone receptor binding; G protein-coupled receptor binding; hormone activity; hormone binding; corticotropin-releasing hormone activity; corticotropin-releasing hormone receptor 1 binding; neuropeptide hormone activity; signaling receptor binding |
| Cellular Localization |
extracellular space; synapse; cytoplasm; neuronal cell body; perikaryon; varicosity; extracellular region |
| Processes |
adenylate cyclase-activating G protein-coupled receptor signaling pathway; cell population proliferation; cellular response to nutrient levels; digestion; hormone-mediated signaling pathway; negative regulation of follicle-stimulating hormone secretion; negative regulation of gene expression; negative regulation of luteinizing hormone secretion; female pregnancy; inflammatory response; negative regulation of epinephrine secretion; negative regulation of glucagon secretion; positive regulation of corticotropin secretion; positive regulation of cortisol secretion; regulation of NMDA receptor activity; synaptic transmission; dopaminergic; adrenal gland development; associative learning; cellular response to cocaine; cellular response to dexamethasone stimulus; diterpenoid metabolic process; glucocorticoid biosynthetic process; hormone-mediated apoptotic signaling pathway; hypothalamus development; ion homeostasis; learning or memory; locomotory exploration behavior; long-term synaptic potentiation; lung development; negative regulation of cell death; negative regulation of norepinephrine secretion; negative regulation of systemic arterial blood pressure; positive regulation of behavioral fear response; positive regulation of calcium ion import; positive regulation of cAMP-mediated signaling; positive regulation of cell death; positive regulation of cell population proliferation; positive regulation of corticosterone secretion; positive regulation of digestive system process; positive regulation of gene expression; positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of protein phosphorylation; regulation of serotonin secretion; response to cocaine; response to corticosterone; response to drug; response to estrogen; response to ethanol; response to ether; response to immobilization stress; response to pain; steroid metabolic process; ; chemical synaptic transmission; G protein-coupled receptor signaling pathway; negative regulation of circadian sleep/wake cycle; REM sleep; negative regulation of inflammatory response to antigenic stimulus; parturition; positive regulation of circadian sleep/wake cycle; wakefulness; signal transduction |
| Common Name |
Urocortin; Corticoliberin; diuretic hormone |
