Details of family id : FD00029
| Family ID |
FD00029 |
| Protein Name |
Acidic phospholipase A2 2; Group 10 secretory phospholipase A2; Phospholipase A2 SSD387 ; Phospholipase A2 AP-PLA2-II; Phospholipase A2 SSD1043 ; Phospholipase A2 Scol; Basic phospholipase A2; Phospholipase A2 |
| UniProt ID |
Q9W7J3
Q9QXX3
P0DPT7
Q3C2C1
P0DPT9
C1JAR9
Q8AXW7
P00593
|
| Prosequence Length Range (aa) |
6-11
|
| Preproprotein Length Range(aa) |
145-158 |
| Preproprotein pI Range |
4.58-8.74 |
| Preproprotein Molecular Weight Range (D) |
15959.21-17489.75 |
| Prosequence pI Range (D) |
3.67-10.9 |
| Prosequence Molecular Weight Range |
677.84-1402.58 |
| Domains |
cd00125 |
| Organisms |
Pseudonaja textilis (Eastern brown snake); Mus musculus (Mouse); Scolopendra dehaani (Thai centipede) (Scolopendra subspinipes dehaani); Acanthaster planci (Crown-of-thorns starfish); Scolopendra viridis (Giant centipede); Micrurus corallinus (Brazilian coral snake); Bos taurus (Bovine) |
| Functions |
calcium ion binding; phospholipase A2 activity; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine); phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine); toxin activity; 1-alkyl-2-acetylglycerophosphocholine esterase activity; calcium-dependent phospholipase A2 activity; phospholipase activity; phospholipid binding; bile acid binding; signaling receptor binding |
| Cellular Localization |
extracellular region; acrosomal vesicle; extracellular space; lysosome; cell surface |
| Processes |
arachidonic acid secretion; lipid catabolic process; phospholipid metabolic process; axon guidance; cellular response to leukemia inhibitory factor; cholesterol homeostasis; defense response to virus; erythrocyte maturation; fertilization; hair follicle morphogenesis; intestinal stem cell homeostasis; low-density lipoprotein particle remodeling; lysophospholipid transport; macrophage activation; negative regulation of cholesterol efflux; negative regulation of cytokine production involved in inflammatory response; negative regulation of DNA-binding transcription factor activity; negative regulation of inflammatory response; phosphatidic acid metabolic process; phosphatidylcholine catabolic process; phosphatidylcholine metabolic process; phosphatidylethanolamine metabolic process; phosphatidylglycerol metabolic process; phosphatidylserine metabolic process; platelet activating factor catabolic process; positive regulation of acrosome reaction; positive regulation of arachidonic acid secretion; positive regulation of cellular protein metabolic process; positive regulation of lipid storage; positive regulation of prostaglandin secretion; production of molecular mediator involved in inflammatory response; prostaglandin biosynthetic process; regulation of macrophage activation; hemolysis in other organism; antibacterial humoral response; antimicrobial humoral immune response mediated by antimicrobial peptide; defense response to Gram-positive bacterium; fatty acid biosynthetic process; innate immune response in mucosa; positive regulation of fibroblast proliferation; positive regulation of glomerular visceral epithelial cell apoptotic process |
| Common Name |
phospholipase; Secretory phospholipase; Phospholipase |
